A group of uncommon chronic illnesses, eosinophil (E-0-’si-n-o-’fil) associated diseases, are rapidly emerging as a healthcare problem worldwide. Yet, many patients suffering from there diseases go undiagnosed for years due to a lack of information or awareness of these diseases.
* High numbers of eosinophils accumulate in body tissues causing inflammation
* Classified by body tissue where eosinophils accumulate.
* Diagnosed and monitored by tissue biopsies.
* Chronic diseases requiring long term treatment, with no known cure.
* Debilitating diseases leading to missed work, school, social outings.
* Delays in diagnosis are common.
* Causes inflammation and damage to the esophagus, affecting the ability
* Estimated prevalence of more than 1 per 2000
* Increase in new cases (2 – 10 fold) over the past 10 years
* Patients may depend on steroids or medical nutrition therapy through
a feeding tube
Eosinophilic Gastroenteritis (EGE) and Eosinophilic Gastritis (EG)
* Causes inflammation and damage to the stomach and/or small intestine, often
* Estimate prevalence of EGE and EC combined is 1 per 3500
* Causes severe abdominal pain, forceful vomiting and/or diarrhea
* Treatment may involve a limited diet, feeding tube and/or steriods
Eosinophilic Colitis (EC)
* Causes inflammation and damage to the large intestine (colon)
* May be misdiagnosed as Irritable Bowel Syndrome (IBS) or Inflammatory bowel
* Patients may require restricted diet therapy, elemental formula or chronic steroids
Hypereosinophilic Syndrome (HES)
* Diagnosed by very high number of eosinophils in the blood and tissue
* Causes potentially fatal damage to one or more organs in the body (heart, lungs,
Churg-Strauss Syndrome (CSS)
* Eosinophils cause damage to small to medium blood vessels (vasculitis)
* Patient may be initally be diagnosed with severe asthma
* Causes potentially fatal lung, heart, brain or gastrointestinal damage
* Estimated to be 60-80 cases / million asthmatics / year.
Can you say EOSINOPHILIC?
E - O - sin - O - phil - ik
© American Partnership for Eosinophilic Disorders
All rights reserved. Updated 06-01-2011
Used with permission.
What is an Eosinophil?
A type of white blood cell associated with allergies, parasites, and cancers.
What are Eosinophil Associated Diseases?